The U.S. Food and Drug Administration (FDA) warned that topical prescription medications containing flurbiprofen are toxic to animals. Ingesting even a tiny amount can lead to severe sickness and death. The warning comes after several reports of dogs becoming sick and dying after consuming the medicine.
What Is Flurbiprofen?
Flurbiprofen, also known as 5-FU, is a non-steroidal, anti-inflammatory drug (NSAID) sold under brand names Carac, Tolak, Fluoroplex, and Efudex or the generic Fluorouracil Cream USP, per the FDA website. Physicians prescribe it to treat skin cancers like basal and squamous cell carcinomas. Doctors also prescribe it for vitiligo, warts, arthritis, joint pain, and other discomforts and aches.
How to Protect Your Dogs
Pets can be exposed to the medication by licking or biting the tube or licking the skin onto which it’s applied. If you use the medicine, be very careful to keep it away from animals.
Keep medications and empty containers in secure cupboards or drawers out of pets’ reach. Above all, if you use items like a cotton applicator or gloves to apply it, remember to thoroughly clean these or throw them out in a secured trash bin. Wash your hands after application. You might also want to cover any treated areas, if possible. In addition, if any medication gets on the carpet or furniture, clean it right away.
According to the FDA, signs of fluorouracil poisoning typically start within 30 minutes of exposure. These may include:
- Vomiting
- Seizures
- Tremors
- Difficulty breathing
- Lethargy
- Diarrhea
- Drooling
- Lack of balance
If you notice any of the above symptoms, take your pet to a veterinarian or animal hospital, or call a pet poison helpline immediately. There is no antidote, but a veterinarian can take measures to relieve the side effects and save your pet’s life, if possible.
The FDA hasn’t yet received any reports of cat poisoning but warns that the medication is also highly toxic to felines.
